If this value is applied to humans, it may take 191 tablets (200mg/tablet) or a total of 38,160 mg for a 60-kg man to die from acute ibuprofen overdose. How much ibuprofen can kill you? Animal research shows that the lethal dose that kills 50% of test animals (LD50) of oral ibuprofen is 636 mg/kg. If you take too much ibuprofen, unpleasant side effects may develop and this may require immediate medical attention. It may be taken up to a maximum of four doses per day or a total of 3200 mg daily. You must also use the smallest dose necessary to obtain relief from your fever, pain, or swelling.Ĭan you overdose on ibuprofen? For adults, the maximum dose of ibuprofen is 800 milligrams (mg) per dose. It should not be used in larger doses or for longer periods than recommended. However, just like all drugs, it should be taken as directed on the medication’s label, or as your doctor prescribed it. Ibuprofen is considered as a safe drug, and is commonly found in many medicine cabinets.
